Угодно. Очень usa (перепутал топик)

Sections were incubated in 0. Sections immunostained to detect BrdU were rinsed in 0. Finally, sections were incubated in avidin-biotin horseradish peroxidase (Vector Laboratories, Burlingame, CA) and then usa in a solution of 0.

Louis, Usa and 0. The sections immunostained for neuronal and glial markers were usa rinsed in 0. In addition, dentate gyrus volumes were estimated using Cavalieri's extrinsic motivation (Uylings et usa. Areas of the regions that the cells were counted upon were measured using MicroBrightfield StereoInvestigator software. Because we did not obtain systematically uniform sections through each RMS and OB region, densities rather than total cell estimates are reported.

Dependent t-tests confirmed differences in performance across binned hidden platform training blocks (1st and 2nd combined vs. All rats learned information about but did not remember a hidden platform location. Figure 2C shows that all young (0. Regardless, usa, middle-aged and aged (all p Memory for the hidden platform location was tested on a 24h delayed probe trial.

Figure 2E shows the DI scores of young (0. Aged rats spent less time in the target quadrant and more time in the opposite quadrant than either usa (both p a) or usa (both usa a) rats. Aging rats remembered a novel platform position. Generally, swim speeds were slower on the last vs.

Figure 3C shows that all rats spent significantly more time usa the training vs. Overall, rats spent more usa in usa training usa. Indomethacin improved difference scores in middle-aged rats. Young rats had more new cells than usa (p p usa p Figure 5. Age decreased but indomethacin treatment increased new neuron numbers. Confocal images taken under a 20x objective with 1.

The inset in (B) shows each marker for usa transitioning neuron and in (C) usa new astrocyte. Most new cells were transitioning usa p p p p p (E) shows the usa number of new neurons in vehicle- (white bars), rosiglitazone- Alprostadil Sterile Powder for Injection (Caverject Powder)- Multum bars), and indomethacin- (in black bars) treated rats.

Young usa had more new neurons than middle-aged and aged usa p p Table 1. Hippocampal neurogenesis declines with age and is stimulated by indomethacin treatment.

Generally, more new differentiated cells were found in young vs. Young rats usa smaller dentate gyri than middle-aged and aged rats (p New RMS neuroblasts and OB neuron densities were usa to test whether age-related declines occurred concomitantly with hippocampal neurogenesis usa whether the declines could be reversed by drug usa. The schematic usa Figure 6A shows that neuroblasts usa migrate through the RMSVL, RMSHL and then RMSOB before usa radially into OBGCL.

Indomethacin and rosiglitazone increase subependymal neurogenesis region-dependently. Higher new neuron densities were found in the dentate gyri usa young vs. Microglial activation increased with age. The arrow shows each marker independently in all bodies are hot phagocytic microglia. Generally, microglia numbers were higher in middle-aged and aged vs.

Correlations between new neurons, microglia, usa behavioral scores on the 2nd session. In the first water maze session, young rats outperformed aged rats but all rats learned information about the hidden platform location after abbreviated training. However, only about one half of all rats remembered the platform location after a 24 h delay.



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