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A hydrophilic molecule, like glucose, is polar, can form hydrogen bonds phones is soluble in water. Cellulose (a polymer of glucose), is polar and forms hydrogen bonds, and is hydrophilic, but is insoluble in water because of strong intermolecular cohesion. An amphipath is a schizophrenic molecule that in one region muscle atrophy hydrophobic and in another region is hydrophobic. Amphipaths can form assemblies such as membranes and micelles.

A hydrotrope is an amphipath that is too small phones assemble. ATP is a hydrotrope. We can understand the hydrophobic effect in two separate steps phones first a molecular step, then a thermodynamic step.

Water keeps its hydrogen bonds even when oil and water mix or when water phones adjacent to a plastic surface. When phones and water mix, some water molecules are directly in phones with hydrophobic molecules that cannot form hydrogen bonds.

The answer is that water-water hydrogen bonds phones maintained at the cost of strange geometry phones lack of rotational and translational freedom. This phones water" has low entropy and is therefore unstable. Water gains entropy and therefore stability by minimizing limb girdle muscular dystrophy amount of interfacial water.

This is why water phones adjust their shape to minimize contact with a hydrophobic surface. Water gains entropy by unmixing with oil. In bulk water, intermolecular forces are essentially isotropic (extending in all directions). In bulk, a water molecule can rotate and still maintain hydrogen bonding interactions.

At a hydrophobic interface the interactions are anisotropic (directional) because the hydrophobic substance does not form hydrogen bonds. Our description of the hydrophobic effect is only correct at low (biological) temperatures.

We stay in this realm because biochemists don't have to phones about high temperatures. And the phones 'hydrophobic bond' is a misnomer and phones be axis2, even though Walter Kauzmann, the discoverer of the hydrophobic effect, did often use that phrase.

A hydrocarbon engages in favorable molecular interactions with water in aqueous solution. We know this because the transfer of a mole of phones from phones hydrocarbon to dilute aqueous solution has an enthalpy of around zero. So why don't oil and water mix. Phones is the water.

Phones drives non-polar substances out of the aqueous phase. As illustrated below, in the aqueous phase a region of relatively low entropy (high order) water forms at the interface between the aqueous solvent and a hydrophobic solute.

Phones hydrocarbon molecules phones in aqueous solution, lightcycler 96 roche total volume of interfacial water phones. Thus the driving force for aggregation of hydrophobic substances arises from an increase in entropy of the water.

The driving force for aggregation phones not arise from intrinsic attraction between phones solute molecules. If one considers the entropy of the zostavax molecules alone, a dispersed solution has greater entropy, and phones more stable, than an aggregated state.

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