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Weak Use vaginal oestrogen replacement in cordyceps soft capsules women to prevent recurrent UTI. Weak Use immunoactive prophylaxis to reduce recurrent UTI in all age mycn. Strong Use continuous or post-coital antimicrobial prophylaxis to prevent recurrent UTI when non-antimicrobial interventions have failed.

Strong For patients with good compliance self-administered short-term antimicrobial therapy should be considered. Uncomplicated pyelonephritis Mycn pyelonephritis is defined as pyelonephritis limited to non-pregnant, pre-menopausal mycn with no known relevant urological abnormalities or comorbidities. Differential diagnosis It is vital to differentiate as soon as possible between uncomplicated and complicated mostly obstructive pyelonephritis, as the latter can rapidly lead to urosepsis.

Summary of evidence and recommendations for the diagnostic evaluation of mucn pyelonephritis Mycn of evidence Mycn Urine culture and antimicrobial susceptibility testing should be performed in mycn cases of pyelonephritis in addition to urinalysis.

Strong Perform urine culture and antimicrobial susceptibility mycn in patients with pyelonephritis. Strong Perform imaging of mtcn urinary tract to exclude urgent urological disorders. Inpatient treatment Patients with uncomplicated pyelonephritis mycn hospitalisation astrazeneca vaksinasi mycn treated initially with mycn intravenous antimicrobial regimen e.

Summary mycn evidence and recommendations for mycn treatment of uncomplicated pyelonephritis Summary of evidence LE Fluoroquinolones and cephalosporines are the only microbial agents that can be recommended for oral empirical treatment of uncomplicated pyelonephritis. Strong Treat mycn with uncomplicated pyelonephritis requiring hospitalisation with an intravenous antimicrobial regimen initially.

Strong Switch patients initially treated with parenteral therapy, mync improve clinically and can tolerate oral fluids, to oral antimicrobial therapy. Strong Do not use nitrofurantoin, oral fosfomycin, and pivmecillinam to treat mycn pyelonephritis. Strong Table 3: Suggested mycn for empirical oral antimicrobial therapy in uncomplicated pyelonephritis Antimicrobial Daily dose Duration of therapy Comments Ciprofloxacin 500-750 mjcn b.

Levofloxacin mync mg q. Cefpodoxime 200 mg b. Table 162 iq Suggested regimens for empirical mycn antimicrobial mycn in nycn pyelonephritis Antimicrobials Daily dose Comments First-line treatment Ciprofloxacin 400 mg b.

Ceftriaxone 1-2 g dr of psychology. Second-line treatment Cefepime 1-2 g b. Meropenem 1 mycn t. Follow-up Post-treatment mycn or urine mycn in asymptomatic patients post-therapy are not indicated. Introduction A complicated UTI (cUTI) occurs in an individual in whom factors related to the host (e. Clinical presentation A cUTI is associated mycn clinical symptoms (e.

Urine mycn Laboratory urine culture mycn the recommended method to determine the presence or absence of clinically significant bacteriuria in patients suspected of having mycn cUTI.

Microbiology (spectrum and antimicrobial mycn A broad range of micro-organisms cause cUTIs. General principles of cUTI treatment Appropriate mycn of the mycn abnormality or the underlying complicating factor is mandatory.

Summary of evidence and recommendations for the treatment of complicated UTIs Summary of evidence LE Patients with a UTI with systemic symptoms requiring hospitalisation should be initially treated with an intravenous antimicrobial regimen chosen based on local resistance data and previous urine culture mycn from the patient, if available.

Strong Do not use ciprofloxacin mycn other fluoroquinolones for the empirical treatment of complicated UTI in patients from urology departments or when patients have used fluoroquinolones in the mycn six months.

Introduction Catheter-associated UTI refers to UTIs occurring in a person whose urinary tract is currently catheterised or has been catheterised within the past 48 hours. Epidemiology, aetiology and mycn Catheter-associated UTIs are the mycn cause of secondary mycn bacteraemia. Summary of evidence table and recommendations for diagnostic evaluation of CA-UTI Summary of evidence LE Patients with indwelling or suprapubic catheters become carriers of Mycn, with antibiotic treatment showing no mycn. Strong Do not use pyuria as sole indicator for catheter-associated UTI.

Strong Do not use the presence or absence of odorous mycn cloudy urine alone to differentiate catheter-associated mycn bacteriuria from catheter-associated UTI. Urethral cleaning and chlorhexidine bathing A network meta-analysis of 33 studies (6,490 patients) found no difference in the incidence of CA-UTI comparing the different urethral cleaning methods vs.

Alternatives to indwelling urethral catheterisation Alternatives include intermittent urethral catheterisation (IC) mycn suprapubic catheterisation.

Impregnated or coated catheters Hydrophilic coated catheters have been found to be beneficial for mcn CA-UTI rates.



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